TF and anemia (phenotype): However, in the longitudinal analysis (using repeated measures of blood lead at 24, 30, 36, 42, and 48 months of age) adjusting for covariates (maternal blood lead level at delivery and child’s concurrent anemia status), the relationship between HFE genotype and blood lead was statistically significant (β = 0.11, p = 0.04), and the relationship between TF genotype and blood lead was borderline significant (β = 0.10, p = 0.08) (Table 5).