TH and hypothyroidism: In utero and lactational exposures to TCDD have been reported to induce thyroid gland hyperplasia (Nishimura et al. 2003) or to induce the liver uridine diphosphate glucuronosyltransferase 1 family that catalyzes TH (Nishimura et al. 2005), which could induce hypothyroidism.