For the regulated genes, the expected shift in polyribosome profile was observed (PDCD8 shifted towards higher fractions in IPF (Figure 4A); CFL2 shifted towards lower fractions in IPF (Figure 4B); and the negative control (FUT10) displayed a similar pattern in IPF and control (Figure 4C)). The gene discussed is CFL2; the disease is idiopathic pulmonary fibrosis.