Baseline and repeat weight, height and waist circumference, serum fasting lipid and hepatic enzyme levels, thyroid panel (for quetiapine). Fasting glucose level monitoring for the risk of diabetes; diet and exercise management. Monitor quarterly or as indicated for movement disorders with the Abnormal Involuntary Movement Scale (AIMS). Prolactin blood level monitoring in the presence of abnormal sexual signs and symptoms. The gene discussed is PRL; the disease is movement disorder.