The fusion cells have inferior ability to stimulate the proliferation of T cells (Figure 3C) that expressed lower levels of IFN-γ (Figure 3D) and to induce CTL responses against the HCC cells (Figure 3E), suggesting that the soluble factors in the supernatant inhibit the maturation of fusion cells and have a negative impact in the stimulation of T cells. Here, IFNG is linked to hepatocellular carcinoma.