APOE and preeclampsia: Nagy et al. (1998), found a higher incidence of the ApoE e2 allele amongst women with preeclampsia compared to controls. Makkonen et al. (2001) studied 133 women with preeclampsia and, in contrast, found that none of the ApoE alleles were over represented when compared with controls, findings that have been confirmed elsewhere (Belo et al. 2004).