However, a recent microarray study revealedthat (1) PPARγ transcriptlevels in all seven cases of PAX8-PPARγ-containingfollicular carcinomas are more than 10-fold higher than normal thyroid tissues,as determined by both microarray and quantitative RT-PCR analyses; (2) theexpression profile of the fusion-positive follicular carcinomas shows inductionof genes that are involved in fatty acid, amino acid, and glucose metabolicpathways. This evidence concerns the gene PAX8 and thyroid gland follicular carcinoma.