However in families with ovarian cancer a mutation was found in 24/46 (52%) of families with less than four affected members and in 7/14 (50%) families with greater than three affected family members, indicating that the presence of ovarian cancer seems much stronger predictor for finding a BRCA1/2 mutation than the number of breast cancer cases in the family. This evidence concerns the gene BRCA1 and ovarian carcinoma.