Liposomal muramyl tripeptide phosphatidylethanolamine is an activator of monocytes and macrophages and induces the secretion of different cytokines (Interleukin 1[IL 1], IL 6, tumor necrosis factor α [TNFα]), and it has been tested in clinical studies on osteosarcoma patients [47, 48]. Here, TNF is linked to osteosarcoma.