P1- and P2-induced transcripts were expressed from other astrocytic gliomas of the series, which also lacked wild-type TP53. There were seven glioblastoma cases (GB164, GB61, GB131, GB29, GB166, GB16 and GB33) that showed loss of one TP53 allele and mutation of the DNA-binding domain in the retained allele (Ichimura et al, 2000; Backlund et al, 2003). Here, TP53 is linked to glioblastoma.