Although ECE-1 has been reported in a number of cancers (Ahmed et al, 2000; Egidy et al, 2000a, 2000b; Arun et al, 2001; Usmani et al, 2002; Dawson et al, 2004, 2006; Awano et al, 2005; Smollich et al, 2007), specific isoforms present have yet to be identified. The gene discussed is ECE1; the disease is cancer.