Specifically, two polymorphisms in p53, c.97-147ins16bp and p.Arg72Pro have been analysed as putative breast cancer susceptibility variants, although not all studies have yielded consistent results (Weston et al, 1997; Wang-Gohrke et al, 1998; Suspitsin et al, 2003; Damin et al, 2006; Baynes et al, 2007; Costa et al, 2008). Here, TP53 is linked to breast cancer.