CXCR4 and colorectal carcinoma: Ottaianoand colleagues found that CXCR4 was overexpressed in human colorectal carcinomatissues compared to normal tissues [40].Cell-surface CXCR4 protein was also expressed at high levels on SW620,SW48, and SW480 colorectal carcinoma cells, and at moderate levels on Caco-2and LoVo cells.