This is consistent with the observation that CCR5 and its ligands associate with a wide array of immunological responses relevant to HIV-AIDS pathogenesis, including cell-mediated immunity, T cell regeneration, activation-induced cell death, and formation of the immunological synapse [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]. Here, CCR5 is linked to AIDS.