We have systematically analyzed the mRNAs associated with the two human Pumilio RNA-binding proteins, PUM1 and PUM2 in HeLa S3 cancer cells, using a method that combines the recovery of endogenous RNP complexes and DNA microarray analysis of the associated mRNAs [2], [44], [60], [61], [62]. This evidence concerns the gene RNPC3 and cancer.