The mean of EGFR RNA level was higher in MPNSTs than in benign dermalneurofibromas (1.68 ± 2.5 versus 1 ± 0.4, NS), and four (25%) of MPNST samplesshowed marked increases of EGFR transcripts(more than 3 times higher than the mean for benign dermal neurofibromas). Here, EGFR is linked to malignant peripheral nerve sheath tumor.