PPARD and malignant colon neoplasm: Its high expression in colon has beenshown to promote colon cancer [12, 13], in a mechanism that involvesthe stimulation of PPARβ/δ by arachidonic acid, PPARβ/δ-dependent upregulationof cyclooxygenase (COX)-2 leading to overproduction of prostaglandin (PG)E2,and PGE2-induced growth of colon cancer cells.