For example, CA125, KLKs 5, 6, 10, B7-H4 and Spondin-2 baseline values (c0) predicted a worse overall survival (Table 2) and CA125, KLKs 5, 6, 10, 11, B7-H4 and Spondin-2 baseline values (c0) a worse progression-free survival of ovarian cancer patients (Table 3). The gene discussed is SPON2; the disease is ovarian carcinoma.