PKC β gene expression was significantly increased in the LN and MPGN groups compared to the diabetic nephropathy group (41.01 ± 14.03 and 39.93 ± 16.41 μg/ml, respectively, vs. 18.20 ± 4.91 μg/ml, p < 0.05). This evidence concerns the gene PRKCB and diabetic kidney disease.