PKC α gene expression was significantly increased in diabetic kidneys compared to LN and MPGN (316.95 ± 152.94 μg/ml vs. 185.97 ± 32.13 and 195.46 ± 46.45 μg/ml, p < 0.05). The gene discussed is PRRT2; the disease is primary membranoproliferative glomerulonephritis.