CD52 and mature T-cell and NK-cell non-Hodgkin lymphoma: The authors found that CD52 is expressed in approximately 40% of PTCL/NOS at the same level as in normal T lymphocytes, being aberrantly downregulated in the remaining cases. Notably, they concluded that the estimation of CD52 expression may provide a rationale for the selection of patients with a higher probability of response to the anti-CD52 antibody alemtuzumab.