IL6 and neoplasm: Indeed, IL-6-neutralising antibodies were able to restore Mage-b-specific immune responses in draining LNs of 4T1 tumour-bearing mice in vitro when restimulated with Mage-b, whereas purified IL-6 completely prevented the induction of Mage-b-specific immune responses in the spleen of 4T1 tumour-bearing mice, when restimulated with Mage-b.