NRXN1 and autism: Similarly, one of two chromosomal rearrangements affecting the NRXN1 gene were also shown to be paternally inherited in one patient.44 The same study also reported two rare missense variants (L18Q and L748I) in 2 of 57 people with ASD.44 People with autism carrying the S14L mutations apparently have seizures and facial dysmorphisms.43 No clinical and family data were reported for patients carrying the insertion.