Of the SNPs analyzed, only the IL6 SNP rs2069832 (C allele; overall frequency: African-Americans = 92%, Caucasians = 55%) was found to be significantly associated with stroke, and this was only among African-Americans (Age-adjusted model: OR = 2.2, 95% CI = 1.0–5.0, p = 0.049; Risk Factor model: OR = 2.5, 95% CI = 1.0–6.5, p = 0.05). The gene discussed is IL6; the disease is Stroke.