Grommes et al. reported that the nonthiazolidinedionetyrosine-based PPARγligand GW7845 reduced viability of rat C6 and human glioma cells and inducedapoptotic cell death in a PPARγ-dependentmechanism as shown by the inhibition of these effects by the specificantagonist GW9662 [51]. The gene discussed is PPARG; the disease is central nervous system cancer.