Analysis of BAT1 mRNA levels (Figure 2) revealed significantly elevated mRNA levels for BAT1 normalized against β-ACTIN (a) while normalization with GAPDH (b) showed marginal significance for increased BAT1 mRNA levels in the AD brains (Mann-Whitney U test: P = .037 and P = .057 respectively). This evidence concerns the gene DDX39B and Alzheimer disease.