Of note, none of the recent genome-wide association studies identified variants in ENSG00000196401 as being related to CHD risk.[46]–[48] It is therefore unlikely that the variant we have examined here (rs1130864) is linked via alternative molecular genetic pathways to CHD risk in such a way that these alternative pathways completely counter balance an important circulating CRP causal effect on CHD. This evidence concerns the gene CRP and coronary artery disorder.