In line with this hypothesis, the morphological and clinical picture of dilated cardiomyopathy in humans is associated with altered Csrp3/Mlp expression [13] and Csrp3/Mlp mutations were found in families suffering from dilated as well as from hypertrophic cardiomyopathy [14,15]. This evidence concerns the gene CSRP3 and hypertrophic cardiomyopathy.