A connection between another tumor suppressorgene (p53) and PPARγ ligands has also been demonstrated by showing that 15-deoxy-PGJ2, togetherwith docetaxel, stimulates apoptosis in NSCLC through inhibition of Bcl2 andcyclin D1 and overexpression of caspases and p53 [34]. This evidence concerns the gene TP53 and non-small cell lung carcinoma.