Compared with normal L2 tissue, there was a four-fold increase in the amount of lactate in the MMTV-c-ErbB2 tumours and a six-fold increase in the bitransgenic tumours (Figure 6c) (p < 0.00001 between L2 and both tumours and p < 0.02 between ErbB2 and bitransgenic tumours, all n = 5). Here, ERBB2 is linked to neoplasm.