ERBB2 and neoplasm: This increase in tumour glycolytic activity was accompanied by significantly decreased intratumuor concentrations of glucose: 1.10 nmol/mg in the L2 mammary gland, 0.46 nmol/mg in ErbB2 tumours (p < 0.01) and 0.14 nmol/mg in bitransgenic tumours (p < 0.0004) (Figure 6d).