Anti-TNFα treated mice also showed reduced numbers (34.3±4.49 adenoma, n = 8, P<0.0001, unpaired t test with Welsh correction) and sizes of polyps (1.516±0.022 mm in diameter, P<0.0001 unpaired t test with Welsh correction, n = 6) (Fig. 6c) as compared to untreated APCΔ468 mice. Here, TNF is linked to adenoma.