Lower perforin and granzyme A expressing CD8+ T-cells also were seen in both groups (Table 2, Figure 1(n)), but the differencewas only statistically significant for the HIV negative groups (P = .01).Additional aflatoxin associated differences among HIV positive participantsincluded lower percentage ofCD4+CD25+CD45RO+ regulatory T-cells (P = .009), which was associated with HIVinfection in both high and low AF-ALBHIV positive participants (Table 2, Figure 1(k)), and lower percentageof naive CD4+ (CD4+CD45RA+CD62L+) T-cells (Table 2, Figure 1(e)) in the highAF-ALB group. This evidence concerns the gene CD8A and HIV infectious disease.