Insulin glargine is currently not recommended by the National Institute for Health and Clinical Excellence (NICE) for routine use for people with Type 2 diabetes, but can be considered for people with Type 2 diabetes who require assistance from a third party to administer their insulin injections, who have recurrent symptomatic hypoglycaemic episodes or who would otherwise need twice-daily basal insulin injections in combination with oral antidiabetic drugs. This evidence concerns the gene INS and type 2 diabetes mellitus.