CD8A and cytomegalovirus infection: The relationship between the CD8 T-cells and CMV is evidently complex, as while a strong CD8 T-cell response is unable to prevent viral excretion in healthy individuals [4] or CMV-associated pathology in renal transplant recipients [2], immunity to chronic CMV infection following bone marrow transplant has been re-established by reconstitution of the CD8 T-cell clones specific for CMV [10].