MDK and neuroblastoma: Midkine protein expression was reported to be correlated with poor prognosis in patients with neuroblastomas (Nakagawara et al, 1995), astrocytomas (Mishima et al, 1997), pancreatic head carcinomas (Maeda et al, 2007), or gastrointestinal stromal tumours (Kaifi et al, 2007).