Therefore, measuring serum 25-OHD3, calcium in 24 hours urine, serum creatinine, TSH, PTH as proposed by Tannenbaum et al. is indicated in patients with osteoporosis and a recent clinical fracture, and enabled us to identify 47 (96%) newly diagnosed contributors and 13 of the 14 laboratory abnormalities [3]. The gene discussed is PTH; the disease is osteoporosis.