Their results indicated that: (1) NRIP contains 860 amino acids and its expression is in the cell nucleus; (2) NRIP binds to both AR and GR and functions as a nuclear receptor co-activator, so it may be a transcriptional cofactor of steroid receptors; and (3) by using a specific NRIP siRNA targeting sequence, it could knock down endogenous and exogenous NRIP gene expression, resulting in significantly diminished cell proliferation in prostate (LNCaP) and cervical (C33A) cancer cells [1,2]. Here, DCAF6 is linked to cancer.