Similar effects were observed following oral or intracerebrovascularadministration ofPPARγ agonists [55, 56].TZD-unrelated PPARγ agonist L-796,449 decreasesinfarct size and improves neurological scores after MCAO in the rat brain [57].Treatment with PPARγ antagonist T0070907 increasedthe infarct size and reversed rosiglitazone-induced protection after stroke. This evidence concerns the gene PPARG and Stroke.