CDKN2A and ovarian neoplasm: Diffuse (>75% positive tumor cells), moderate to strong p16 expression is a sensitive (100%) and specific (97%) marker for identifying HPV-related endocervical ade-nocarcinomas metastatic to the ovary among the primary ovarian tumors and metastatic adenocarcinomas from other sites that are in the differential diagnosis of ovarian tumors having mucinous and/or endometrioid/endometrioidlike differentiation.