In addition, there was no significant difference in the mean ADA value in patients with lower CD4 counts (81 U/L±55.1); (76 U/L±45.3) compared to those with higher CD4 cell counts (70 U/L±37.8); (72 U/L±40.6), (p>0.5) among confirmed and total TB pleuritis respectively. The gene discussed is ADA; the disease is Pleuritis.