The CAPN10 gene was identified as a type 2 diabetes (T2DM) susceptibility locus by Horikawa et al. [26] and, since then, has been associated with many other related conditions such as polycystic ovary syndrome (PCOS), dyslipidemia, hypertension or increased BMI by different groups [24]. Here, CAPN10 is linked to type 2 diabetes mellitus.