EFNA2 and cancer: To test if our findings in mouse cells also apply to human cells we immunoprecipitated HuR from the cervical carcinoma cell line HeLa and the astrocytoma/glioblastoma cell line U373MG (Fig. 5a) using an anti-HuR antibody, and performed RT-PCR on the immunoprecipitate with primers specific for EfnA2, EphA2, and EphA4, which are three mRNAs known to be highly expressed in various cancer types [11].