Numerous genes that are up- or downregulated in PCa have been identified with α-methylacyl-CoA racemase (AMACR) (Rubin et al, 2002), prostate-specific membrane antigen (PSMA) (Burger et al, 2002), Hepsin (Stephan et al, 2004), DD3/PCA3 (Hessels et al, 2003) and hTERT (Sommerfeld et al, 1996) among the more common (Ross et al, 2003). The gene discussed is AMACR; the disease is posterior cortical atrophy.