Genes involved in that process were EDN1, GADD45A, IL1A, MT2A, PTHLH, REN, RRM2B, SERPINE1, THBS1, TGFB1, UPK2, and VEGF. Other highly significant functions were "cancer growth of tumor cell lines" (P = 1.99 × 10-7), and "cellular growth" and "proliferation" (colony formation of eukaryotic cells) (P = 5.94 × 10-7). Here, GADD45A is linked to neoplasm.