LOXL1 and exfoliation syndrome: Thorleifsson et al. [7], in 2007, demonstrated that two single nucleotide polymorphisms (SNPs), rs1048661 (R141L) and rs3825942 (G153D), in exon 1 of the lysyl oxidase-like 1 (LOXL1) gene confer risk of XFG, possibly through XFS, in patients from Iceland and Sweden.