In order to validate the GAPF results for the bic locus, and gain an initial insight into the structure of palindromes formed near bic, we carried out blot-hybridization studies of DNA from normal bursa, DT40 cells and bursal lymphoma from an in-vivo tumor before and after the snap-back procedure and digestion with S1 nuclease. This evidence concerns the gene MIR155HG and neoplasm.