However, the analysis of the group of 66 patients that were followed up for 18 months shows that when we retrospectively calculated the mean values of plasmatic concentration of neurosin in MCI patients who converted to each group there were significant differences between those who converted to Dementia with vascular component (mean: 7.17 ng/ml), those who converted to AD (mean: 4.96 ng/ml) (p = 0.015), and those who remained at MCI stage (mean: 5.03 ng/ml) (p = 0.036) (Figure 1). The gene discussed is KLK6; the disease is dementia.