PPARG and thyroid cancer: Moreover, overexpression of PPARγ in thyroid cancer cells significantlyincreased apoptosis compared to cells transfected with empty vector or with avector carrying a mutated nonfunctional PPARγ cDNA [10].Collectively, it appears that the presence of PPARγ at least partly contributes to the inductionof apoptosis by PPARγ ligands in thyroid cancer.