Our own studies have demonstrated that PPAR-γ is expressed in the nucleus of six humanpancreatic cancer cells and that treatment of these cells in vitro with15-deoxy-Δ12,14-prostaglandin J2 (15-PGJ2) andciglitazone dose- and time-dependently decreases cell growth by induction ofcaspase-3-dependent apoptosis [40]. Here, PPARG is linked to cancer.