LGALS4 and colitis: Using in situ BrdU labeling, we could demonstrate, that in response to DSS application, BrdU is found within the epithelial, but also sub-epithelial compartment but, congruently with the in vitro results, cell expansion in Gal-4 treated animals was clearly inhibited, again confirming the applicability of this colitis model and the transmissibility of the in vitro data to the in vivo model (Fig 6D, E).