In the QFT-IT assay mean (SEM) IFN-γ responses to ESAT-6, CFP-10 and TB 7.7 were also significantly higher in children with TB disease compared to those with latent TB infection (12.44 (1.9) vs. 4.65 (1.06) IU/ml, p = 0.002). The gene discussed is IFNG; the disease is tuberculosis.